A Tail of Phage Adhesins

Llama antibodies against a lactococcal protein located at the tip of the phage tail prevent phage infection.

Bacteriophage p2 belongs to the most prevalent lactococcal phage group (936) responsible for considerable losses in industrial production of cheese. Immunization of a llama with bacteriophage p2 led to higher titers of neutralizing heavy-chain antibodies (i.e., devoid of light chains) than of the classical type of immunoglobulins. A panel of p2-specific single-domain antibody fragments was obta...

Isolation and characterization of a phage active against streptomyces griseus

Puzzling Peptides from a Phage Display Library

The commercial availability of random peptide libraries displayed on the M13 phage is increasing their use forstudies on epitope identification, enzyme inhibitors, receptor ligands, etc. In this study two experimentswhere planned for selection of peptides. First with sheep antibodies, the positive selector was IgG, preparedon Protein G column from a pool of 11 sheeps immunized...

Characterization of maltocin P 28 , a novel phage tail - like bacteriocin from 1 Stenotrophomonas maltophilia

24 Stenotrophomonas maltophilia is an important global opportunistic pathogen for which 25 limited therapeutics are available because of the emergence of multidrug-resistant strains. 26 A novel bacteriocin, maltocin P28, which is produced by S. maltophilia strain P28, is the 27 first-identified phage tail-like bacteriocin from S. maltophilia. Maltocin P28 resembles a 28 contractile but non-flex...

Characterization of maltocin P28, a novel phage tail-like bacteriocin from Stenotrophomonas maltophilia.

Stenotrophomonas maltophilia is an important global opportunistic pathogen for which limited therapeutics are available because of the emergence of multidrug-resistant strains. A novel bacteriocin, maltocin P28, which is produced by S. maltophilia strain P28, may be the first identified phage tail-like bacteriocin from S. maltophilia. Maltocin P28 resembles a contractile but nonflexible phage t...